Download e-book for iPad: Advances in Intravital Microscopy: From Basic to Clinical by Roberto Weigert

By Roberto Weigert

ISBN-10: 9401793603

ISBN-13: 9789401793605

ISBN-10: 9401793611

ISBN-13: 9789401793612

This is the 1st e-book totally devoted to Intravital Microscopy. It offers the reader with a wide review of the most functions of Intravital Microscopy in a variety of parts of the biomedical box. The booklet includes exact descriptions of the state-of-the-art methodologies used to photo a number of organs at assorted point of solution, starting from complete tissue right down to sub-cellular buildings. furthermore, it really is a very precious consultant to scientists that are looking to undertake this strong strategy and don't have event with animal versions and microscopy.

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Additional info for Advances in Intravital Microscopy: From Basic to Clinical Research

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RBCs and plasma, for each vessel (Fig. 3c, right panel). Flux is a more complete description of blood flow in single vessels, as RBC velocity and lumen diameter can change independently of each other (Shih et al. 2009; Kontos 1989). The volume flux through the vessel is given by  p  F = 〈 v〉 A = v ( 0 ) d 2 8 where 〈 v 〉 is the average RBC velocity over A, the cross-sectional area of the vessel lumen, v(0), is the time-averaged RBC velocity at the center line of the vessel, and is the lumen diameter.

Summers et al. a b λ Thinned skull Cover glass β Cortex Head fix bar Dental cement Dental cement Cover glass Cyanoacrylate glue Skull Dura mater 1 mm c 1 mm Fig. 2 Polished and reinforced thinned-skull transcranial window for imaging mouse cortex. (a) Schematic diagram showing dorsal view of the head mount and position of various components. A cross bar mount is added for stability when imaging awake preparations. β bregma and λ lambda. (b) Schematic diagram showing cross section of a PoRTS window and the components involved in its construction.

S. from the National Institutes of Health for generous support (1R21NS085402-01), Dana Foundation (David Mahoney Neuroimaging Program) and South Carolina Clinical and Translational Institute (UL1TR000062). References Alkire MT, Haier RJ, Barker SJ, Shah NK, Wu JC, Kao YJ (1995) Cerebral metabolism during propofol anesthesia in humans studied with positron emission tomography. Anesthesiology 82(2):393–403 Antognini JF, Buonocore MH, Disbrow EA, Carstens E (1997) Isoflurane anesthesia blunts cerebral responses to noxious and innocuous stimuli: a fMRI study.

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Advances in Intravital Microscopy: From Basic to Clinical Research by Roberto Weigert


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